皰疹病毒2IgM(HSV 2-IgM)
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意大利進(jìn)口TORCH試劑
測(cè)IgM為較受推崇的抗體捕獲法，測(cè)IgG為6點(diǎn)定標(biāo)的定量間接法，總準(zhǔn)確率可達(dá)到98~100%
不同品種操作完全一致，已稀釋樣本可多項(xiàng)檢測(cè)
樣本溫育只需45分鐘(在同類產(chǎn)品中時(shí)間最短)
全部操作流程只需2~3小時(shí)(取決于樣本量)，即使開(kāi)展全部8項(xiàng)檢測(cè)亦可在半個(gè)工作日內(nèi)輕松完成
底物為單一底物液，簡(jiǎn)化操作，減少誤差
稀釋液、洗滌液、底物液、終止液均可通用
試劑及包裝均有顏色標(biāo)記，減少操作失誤
單純皰疹病毒2型IgM抗體HSV 2-IgM
酶聯(lián)免疫吸附測(cè)定法（ELISA）試劑盒
捕獲法
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用途
?單純皰疹病毒2型IgM抗體HSV 2-IgM酶聯(lián)免疫吸附測(cè)定法（ELISA）試劑盒用于體外半定量檢測(cè)人血清中的HSV 2 IgM抗體，并輔助診斷皰疹相關(guān)性疾病。高度復(fù)雜的檢測(cè)。
1.?????? 引言
在全世界范圍內(nèi)都存在人類的單純皰疹病毒（HSV）感染。HSV感染的臨床病程差異很大，而大多數(shù)病例為癥狀輕微的隱性感染（通常不能察覺(jué)）。臨床征象明顯的HSV感染表現(xiàn)不一，既可為輕微的咽炎，又可為致死性的嚴(yán)重泛發(fā)性疾病。與HSV感染有關(guān)的主要臨床疾病為齦口炎、角膜炎、結(jié)膜炎、皮膚皰疹、無(wú)菌性腦膜炎、腦炎、生殖道感染以及新生兒皰疹。新生兒感染可局限在皮膚，或者泛發(fā)，嚴(yán)重累及中樞神經(jīng)系統(tǒng)、眼、皮膚以及其他器官。
單純皰疹病毒有兩種類型，它們?cè)谛螒B(tài)學(xué)上無(wú)法區(qū)分，而且約40%的DNA堿基序列相同，有許多共同抗原，可產(chǎn)生相同的皮膚和粘膜病變?？赏ㄟ^(guò)其抗原、生物學(xué)、生物化學(xué)以及臨床和流行病學(xué)行為的差別來(lái)區(qū)分這兩種類型的病毒。HSV 2通過(guò)性傳播，或由母親的生殖器感染傳遞給新生兒。它可導(dǎo)致大多數(shù)生殖器皰疹、新生兒皰疹以及腰部以下的皮膚感染。HSV 1主要通過(guò)非性途徑來(lái)傳播，通常是由于接觸了感染者的唾液而受到傳染。除新生兒皰疹之外，兒童時(shí)期的大多數(shù)HSV感染均是由HSV 1引致的。性行為是HSV 2感染傳播的途徑，因此在開(kāi)始性行為之前，很少發(fā)生HSV 2感染（1，2，3，4，5，6）。
大多數(shù)人在20歲之前就已感染過(guò)HSV（7，8）。因此，任何血清學(xué)方法檢測(cè)到的血清中抗HSV抗體均不能提示感染的時(shí)間，除非進(jìn)行特異性IgM抗體檢測(cè)。HSV初次感染之后，抗體水平逐漸下降至較低或檢測(cè)不到的水平，以后如果發(fā)生同一類型或不同類型的臨床感染，抗體會(huì)受到刺激而再次抬升。
初次感染是針對(duì)以前未感染過(guò)HSV 1或HSV 2的個(gè)體而言。已經(jīng)知道，過(guò)去感染過(guò)HSV 1并不能保護(hù)該個(gè)體不會(huì)受到HSV 2的感染；然而，如果以前曾感染過(guò)HSV 1，而后又發(fā)生了HSV 2感染，這類患者的臨床表現(xiàn)會(huì)有所減輕（7）。
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2.?????? 參考文獻(xiàn)
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